How Diet Influences Cancer Risk
Alex Fir
Diet is a double edged sword. Improper diet increases the risk of
cancer but a proper, well balanced diet reduces the cancer risk.
Diet is one of the most important lifestyle factors and has been
estimated to account for up to 80% of cancers of the large bowel,
breast, and prostate. Diet affects the risk of many other cancers,
including cancers of the lung, prostate, stomach, esophagus and
pancreas.
Prostate Cancer:
High consumption of meat, especially red meat, substantially increases
the risk of prostate cancer.
Vegetables, especially cooked tomatoes, reduce the risk of prostate
cancer. In one clinical trial, the role of Vitamin E as a prostate
cancer reducing factor was established. In this study there was a 32%
decrease in prostate cancer incidence and 41% decrease in prostate
cancer mortality in people receiving Vitamin E supplements when
compared to controls.
Breast Cancer:
In Japan, people consume Tofu, a soya product. It contains isoflavones
that moderate the estrogen receptors in the body such as breast tissue.
The incidence of breast cancer is low in Japan when compared to Western
women; only 1/4th of the mortality rate of Western women. Japanese
women's low fat diet, high fish consumption and drinking green tea also
decrease their breast cancer risk.
One case control study found that regular consumption of soy foods was
associated with a marked decrease in breast cancer risk in
premenopausal women. No effect in post-menopausal women.
A Japanese case-control study also found that tofu intake (3 times/wk
compared with less than 3 times/wk) was associated with decreased risk
of breast cancer in premenopausal women. Again, soy intake was not
protective against post-menopausal breast cancer.
In one study conducted in America, the relation between soy intake and
breast cancer risk found that tofu consumption was protective in both
premenopausal and post menopausal Asian women.
Lung Cancer:
Lung cancer risk is substantially decreased by a variety of
carotenoids. Carotenoids act as antioxidants and thus minimize cell
damage.
One study in Boston focused on the effect of different types of
carotenoids on lung cancer risk. It was observed that lung cancer risk
was significantly lower in subjects who consumed a diet high in a
variety of carotenoids. This was especially true with non-smokers who
had 63% less risk.
One study conducted in Hawaii reported further evidence for a
protective effect from certain carotenoids against lung cancer and that
greater protection was afforded by consuming a variety of vegetables
compared to only foods rich in a particular carotenoid.
Stomach Cancer:
Nitrates in food and other preservatives added to food including meat
are converted into 'nitrites' in the human stomach. The nitrites
undergo nitrosation to form 'nitrosamines' and 'nitrosamides'. This
increases the risk of stomach cancer in people eating vegetables from
nitrate rich soil.
In one study, Vitamin C appeared to protect against the risk of stomach
cancer by inhibiting formation of nitrates in stomach.
Cancer of the stomach is 5 times more common in Japanese people
compared to Western populations. When Japanese people migrated to the
United States, they progressively acquired the low incidence of the US
due to changes in their diets.
In one study conducted in Hawaii that involved both Japanese and
Caucasians, the stomach cancer risk was associated with consumption of
rice, pickled vegetables, and dried/salted fish, and a negative
association with vitamin C intake.
One ecological study in Belgium showed a relation between the nitrate
and salt consumption and stomach cancer. The analysis of this model
showed that the significance of nitrate as a risk factor for stomach
cancer mortality increased markedly with higher sodium levels.
Dietary habits and stomach cancer risk was studied in Shanghai, China.
According to this study, risks of stomach cancer were inversely
associated with high consumption of several food groups, including
fresh vegetables and fruits, poultry, eggs, plant oil, and some
nutrients such as protein, fat, fiber, tea and antioxidant vitamins.
By contrast, risks increased with increasing consumption of dietary
carbohydrates, frequent consumption of preserved, salty or fried foods
and hot soup/porridge, with irregular meals, speed eating and binge
eating. This provides evidence that diet plays a major role in stomach
cancer risk.
No single food can completely prevent cancer but a balanced combination
of different groups can help. Appropriate diet can prevent 3-4 million
cancers each year.
About the Author: Cancer is One of the Main Causes of Death Among
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